Journal: Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Article Title: Longitudinal measurement of serum cartilage oligomeric matrix protein can detect the progression of cartilage degeneration in anterior cruciate ligament reconstruction patients
doi: 10.1016/j.asmart.2024.06.003
Figure Lengend Snippet: Receiver operating characteristic curve analysis was used to determine the cutoff value of statistically significant variables in diagnosing detecting the progression of cartilage degeneration. The cutoff value for the increase in serum COMP to detect the progression of cartilage degeneration was 1.24-fold increase. The sensitivity was 87.5 %, and the specificity was 73.9 %. AUCs were also calculated to estimate the diagnostic accuracy of serum COMP level. The AUC value of change of serum COMP was 0.766.
Article Snippet: Enzyme-linked immunosorbent assay was used to measure serum COMP levels (#DCMP0; R&D Systems, Minneapolis, MN).
Techniques: Diagnostic Assay